Leverage national medico-administrative data for your epidemiological, health economics, and pharmacoepidemiological studies.
The Programme de Médicalisation des Systèmes d'Information (PMSI) records all French hospital activity across 4 complementary fields.
Medicine, surgery, obstetrics, and odontology. The primary field covering acute hospital stays with ICD-10 diagnoses and CCAM procedures.
Diagnoses · Procedures · GHM/GHSFollow-up and rehabilitation care. Post-hospitalisation rehabilitation stays with specific coding of impairments and dependencies.
Rehabilitation · DependencyHome hospitalisation. Hospital-level care delivered at the patient's home, with tracking of care modes and diagnoses.
Home care · Follow-upMental health institutions. Psychiatric activity data for full or partial inpatient stays, with diagnostic coding.
Mental health · StaysThe pharmaceutical industry accesses exhaustive PMSI data through the CNIL reference methodology MR-006. Data are processed within the secure CASD environment.
MR-006 is the CNIL reference methodology governing access to PMSI data by healthcare industry players. It allows a compliance declaration without an individual authorisation.
PMSI data are processed within the CASD (Centre d'Accès Sécurisé aux Données), a public-interest group offering a highly secure environment for processing confidential data.
Access to PMSI data follows a structured process, from protocol drafting to data analysis within the secure CASD environment.
Clinityx manages the entire process: scientific scoping, regulatory file, data order from ATIH, analysis at CASD, and deliverable production.
The eSND is a representative 1-in-50 sample of the French population, combining hospital data and outpatient care. It benefits from a simplified access procedure via the Health Data Hub.
The eSND replaced the former EGB (Échantillon Généraliste de Bénéficiaires) in 2022. It provides a 1-in-50 (2%) population sample, linking outpatient data (DCIR) with hospital data (PMSI).
The eSND benefits from a simplified access procedure, with no individual CNIL authorisation required, subject to compliance with conditions defined by the CNIL.
The eSND is particularly suited to exploratory studies, feasibility analyses, and studies on common conditions where a 2% sample provides sufficient statistical power.
PMSI and eSND data cover a broad spectrum of real-world studies, from descriptive epidemiology to health economic evaluations.
Incidence, prevalence, characterisation of target populations. Identification and sizing of cohorts at national scale using identification algorithms.
Care costs, burden of disease, budget impact. Hospital stay valuation via GHS and analysis of outpatient care consumption.
Real-world treatment use, lines of therapy, persistence and adherence. Post-marketing safety studies and therapeutic strategy comparisons.
Longitudinal analysis of patient trajectories between outpatient and hospital settings. Identification of care gaps and management delays.
Comparison of therapeutic strategies under real-world conditions. Analyses using propensity scores, matching, and causal methods on observational data.
Real-world data for HAS dossiers (ASMR/SMR), CEPS negotiations, and post-listing studies requested by authorities.
Clinityx manages the entire process: scientific scoping, regulatory file preparation, data ordering, and analysis within the appropriate secure environment.
For PMSI, we manage the order with ATIH and analysis at CASD. For eSND, we instruct the request with the Health Data Hub via the simplified procedure.
Definition of the study protocol, objectives, and required data scope. Choice of source (exhaustive PMSI or eSND).
PMSI: MR-006 compliance declaration with the CNIL. eSND: request via the Health Data Hub simplified procedure.
PMSI: order placed with ATIH, data made available at CASD. eSND: instruction by HDH and sample provision.
Development of identification algorithms, cohort structuring, and statistical analyses in the secure environment (CASD for PMSI).
Production of aggregated and anonymised results: study report, scientific publication, market access dossier (HAS/CEPS).
A unique expertise combining mastery of national data, data engineering, and end-to-end regulatory support.
In-depth knowledge of French medico-administrative data, built across numerous studies.
Full management of the authorisation process, from protocol design to data provision.
Production of robust studies, from cohort construction to deliverable writing.
Two complementary data sources, each suited to different needs in terms of scope, exhaustiveness, and access timeline.
| Criterion | PMSI (MR-006) | eSND (simplified proc.) |
|---|---|---|
| Scope | Hospital data | Linked sample (DCIR + PMSI + CépiDC) |
| Population | Exhaustive (all hospitalisations) | ~1.3M beneficiaries (2% sample) |
| Body | ATIH | Health Data Hub |
| Regulatory framework | MR-006 compliance | HDH simplified procedure |
| Processing environment | CASD | HDH platform |
| Care pathways | Hospital only | Complete (outpatient + hospital) |
| Outpatient medications | No | Yes (DCIR) |
| Causes of death | No | Yes (CépiDC) |
| Access timeline | 2 to 4 months | A few weeks |
| Typical use cases | Hospital epidemiology, burden of disease, DRG analysis | Exploratory studies, feasibility, care pathways |
From protocol design to results delivery, Clinityx supports you throughout the entire process.